Open AccessMelatonin attenuates cisplatin-induced HepG2 cell deathviathe regulation of mTOR and ERCC1 expressions
Author(s) -
Kangsadarn Bennukul,
Sucha Numkliang,
Vijittra Leardkamolkarn
Publication year - 2014
Publication title -
world journal of hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.913
H-Index - 55
ISSN - 1948-5182
DOI - 10.4254/wjh.v6.i4.230
Subject(s) - melatonin , viability assay , cisplatin , apoptosis , cell cycle , programmed cell death , microbiology and biotechnology , mtt assay , acridine orange , cell growth , biology , medicine , endocrinology , biochemistry , chemotherapy
To elucidate the effects of melatonin on cisplatin-induced hepatocellular carcinoma (HepG2) cell death and to identify potential cross-talk pathways.