Open AccessBinge ethanol intake in chronically exposed rat liver decreases LDL-receptor and increases angiotensinogen gene expression
Author(s) -
Annayya R. Aroor,
Shivendra D. Shukla
Publication year - 2011
Publication title -
world journal of hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.913
H-Index - 55
ISSN - 1948-5182
DOI - 10.4254/wjh.v3.i9.250
Subject(s) - medicine , endocrinology , ethanol , steatosis , binge drinking , liquid diet , ldl receptor , receptor , gene expression , mapk/erk pathway , downregulation and upregulation , kinase , lipoprotein , cholesterol , alcohol , chemistry , gene , biochemistry , alcohol consumption
To investigated the status of low-density lipoprotein (LDL)-receptor and angiotensionogen gene expression in rats treated chronically with ethanol followed by binge administration, a model that mimics the human scenario.