Open AccessConstruction of non-covalent single-chain Fv dimers for hepatocellular carcinoma and their biological functions
Author(s) -
Caiqun Bie,
DongHua Yang,
XuJing Liang,
Shaohui Tang
Publication year - 2010
Publication title -
world journal of hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.913
H-Index - 55
ISSN - 1948-5182
DOI - 10.4254/wjh.v2.i5.185
Subject(s) - linker , recombinant dna , microbiology and biotechnology , blot , phage display , amino acid , immunoglobulin light chain , hepatocellular carcinoma , plasmid , antibody , antigen , expression vector , gene , biology , biochemistry , cancer research , genetics , computer science , operating system
To create new diabodies with improved binding activity to antigen of the variable light - variable heavy (VH-VL) oriented single-chain Fv dimers genes (scFv).