Open AccessPathogenesis of autoimmune hepatitis
Author(s) -
Junhua Fan,
Geng-Feng Liu,
Xiaodan Lv,
Rui-zhi Zeng,
Lijun Zhan,
Xiaoping Lv
Publication year - 2021
Publication title -
world journal of hepatology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.913
H-Index - 55
ISSN - 1948-5182
DOI - 10.4254/wjh.v13.i8.879
Subject(s) - medicine , pathogenesis , autoimmune hepatitis , immunology , etiology , genetic predisposition , immune system , disease , hepatitis , immune dysfunction , viral hepatitis , autoimmune disease , pathology , antibody
Autoimmune hepatitis (AIH) is a chronic progressive liver disease whose etiology and pathogenesis are not yet clear. It is currently believed that the occurrence of AIH is closely related to genetic susceptibility and immune abnormalities, and other factors such as environment, viral infection and drugs that may cause immune dysfunction. This article reviews the pathogenesis of AIH and describes the latest research results in the past 5 years.