Open AccessDrug eluting biliary stents to decrease stent failure rates: A review of the literature
Author(s) -
Joseph J. Shatzel,
Ji-Soo Kim,
Kartik Sampath,
Sharjeel Syed,
Jennifer Saad,
Zilla Hussain,
Kabir Mody,
J. Marc Pipas,
Stuart R. Gordon,
Timothy B. Gardner,
Richard Rothstein
Publication year - 2016
Publication title -
world journal of gastrointestinal endoscopy
Language(s) - English
Resource type - Journals
ISSN - 1948-5190
DOI - 10.4253/wjge.v8.i2.77
Subject(s) - medicine , biliary stent , stent , drug , clinical trial , surgery , pharmacology
Biliary stenting is clinically effective in relieving both malignant and non-malignant obstructions. However, there are high failure rates associated with tumor ingrowth and epithelial overgrowth as well as internally from biofilm development and subsequent clogging. Within the last decade, the use of prophylactic drug eluting stents as a means to reduce stent failure has been investigated. In this review we provide an overview of the current research on drug eluting biliary stents. While there is limited human trial data regarding the clinical benefit of drug eluting biliary stents in preventing stent obstruction, recent research suggests promise regarding their safety and potential efficacy.