Open AccessRussell body duodenitis with immunoglobulin kappa light chain restriction
Author(s) -
William R. Munday,
Lucy Harn Kapur,
Mina L Xu,
Xuchen Zhang
Publication year - 2015
Publication title -
world journal of gastrointestinal endoscopy
Language(s) - English
Resource type - Journals
ISSN - 1948-5190
DOI - 10.4253/wjge.v7.i1.73
Subject(s) - duodenitis , gastritis , medicine , duodenum , helicobacter pylori , gastroenterology , antibody , immunoglobulin light chain , pathology , immunology
Russell bodies are eosinophilic intracytoplasmic globules which are likely the result of disturbed secretion of immunoglobulins that accumulate within the plasma cell. Russell body collections have been identified within the stomach, known as Russell body gastritis. Similar lesions within the duodenum are referred to as Russell body duodenitis, which is rare. Several Russell body gastritis case reports are associated with Helicobacter pylori. However, the etiology of Russell body duodenitis remains unclear. Here we report the first case of Russell body duodenitis with immunoglobulin light chain restriction in a background of peptic duodenitis.