Open AccessMucosal-incision assisted biopsy for suspected gastric gastrointestinal stromal tumors
Author(s) -
Eikichi Ihara,
Hiroshi Matsuzaka,
Kazuo Honda,
Yoshitaka Hata,
Yorinobu Sumida,
Hirotada Akiho,
Tadashi Misawa,
Satoshi Toyoshima,
Yoshiharu Chijiíwa,
Kazuhiko Nakamura,
Ryoichi Takayanagi
Publication year - 2013
Publication title -
world journal of gastrointestinal endoscopy
Language(s) - English
Resource type - Journals
ISSN - 1948-5190
DOI - 10.4253/wjge.v5.i4.191
Subject(s) - medicine , gist , biopsy , endoscopic ultrasound , gold standard (test) , stromal cell , stromal tumor , stomach , radiology , endoscopy , pathology
To evaluate the diagnostic yield of the procedure, mucosal-incision assisted biopsy (MIAB), for the histological diagnosis of gastric gastrointestinal stromal tumor (GIST), we performed a retrospective review of the 27 patients with suspected gastric GIST who underwent MIAB in our hospitals. Tissue samples obtained by MIAB were sufficient to make a histological diagnosis (diagnostic MIAB) in 23 out of the 27 patients, where the lesions had intraluminal growth patterns. Alternatively, the samples were insufficient (non-diagnostic MIAB) in remaining 4 patients, three of whom had gastric submucosal tumor with extraluminal growth patterns. Although endoscopic ultrasound and fine needle aspiration is the gold standard for obtaining tissue specimens for histological and cytological analysis of suspected gastric GISTs, MIAB can be used as an alternative method for obtaining biopsy specimens of lesions with an intraluminal growth pattern.