Open AccessPrimary intestinal follicular lymphoma: How to identify follicular lymphoma by routine endoscopy
Author(s) -
Masaya Iwamuro,
Yosuke Kawai,
Katsuyoshi Takata,
Seiji Kawano,
Tadashi Yoshino,
Hiroyuki Okada,
Kazuhide Yamamoto
Publication year - 2013
Publication title -
world journal of gastrointestinal endoscopy
Language(s) - English
Resource type - Journals
ISSN - 1948-5190
DOI - 10.4253/wjge.v5.i1.34
Subject(s) - esophagogastroduodenoscopy , follicular lymphoma , medicine , pathology , lymphoma , follicular phase , malt lymphoma , endoscopy , pathognomonic , disease
A 69-year-old Japanese female was diagnosed with primary intestinal follicular lymphoma. Esophagogastroduodenoscopy with high-definition imaging revealed not only the typical feature of whitish polyps of up to 2 mm in diameter in the duodenal second and third portions, but also more detailed morphology, such as enlarged whitish villi and tiny whitish depositions. These findings appeared to reflect the pathological structures; infiltration of lymphoma cells into the villi were probably seen as enlargement of the villi, and the formation of lymphoid follicles were shown as opaque white spots or tiny white depositions. Thus, the above features might contribute to the distinct diagnosis of intestinal follicular lymphoma. This case indicates that routine esophagogastroduodenoscopy can visualize microsurface structures, which can be pathognomonic and help to diagnose intestinal follicular lymphoma, even without magnifying endoscopy.