Open AccessEsophagitis dissecans superficialis and autoimmune bullous dermatoses: A review
Author(s) -
Akira Hokama,
Yuichi Yamamoto,
Kaoru Taira,
Mitsuteru Nakamura,
Chiharu Kobashigawa,
Manabu Nakamoto,
Tetsuo Hirata,
Nagisa Kinjo,
Fukunori Kinjo,
Keiichi Takahashi,
Jiro Fujita
Publication year - 2010
Publication title -
world journal of gastrointestinal endoscopy
Language(s) - English
Resource type - Journals
ISSN - 1948-5190
DOI - 10.4253/wjge.v2.i7.252
Subject(s) - medicine , dermatology , pemphigus vulgaris , esophagitis , pathophysiology , bullous pemphigoid , pemphigus , presentation (obstetrics) , pemphigoid , pathology , disease , immunology , surgery , reflux , antibody
Esophagitis dissecans superficialis (EDS) is a rare and severe endoscopic finding characterized by sloughing of large fragments of esophageal mucosal lining. Although EDS has been reported in association with serious illnesses and certain medications, the pathophysiological association of autoimmune bullous dermatoses with EDS has gained remarkable attention. Among these dermatoses, pemphigus vulgaris and pemphigoid frequently present with various types of esophageal involvement including EDS. We review the pathophysiology and clinical features of this involvement with the presentation of our experiences. The importance of endoscopic evaluation of this entity is discussed.