Open AccessCytomegalovirus gastritis
Author(s) -
Akira Hokama,
Kaoru Taira,
Yuichi Yamamoto,
Nagisa Kinjo,
Fukunori Kinjo,
K. Takahashi,
Jiro Fujita
Publication year - 2010
Publication title -
world journal of gastrointestinal endoscopy
Language(s) - Uncategorized
Resource type - Journals
ISSN - 1948-5190
DOI - 10.4253/wjge.v2.i11.379
Subject(s) - medicine , cytomegalovirus , gastritis , ganciclovir , epigastric pain , gastroenterology , prednisolone , erythema , gastrointestinal bleeding , abdominal pain , pathology , stomach , dermatology , human immunodeficiency virus (hiv) , herpesviridae , virus , immunology , human cytomegalovirus , viral disease , vomiting
Cytomegalovirus (CMV) has been increasingly recognized as an important common pathogen in an immunocompromised state. The colon and stomach are the most common sites of its gastrointestinal infection. Symptoms of CMV gastritis are usually nonspecific and include epigastric pain, fever, nausea and bleeding. Endoscopic features are quite variable and include macroscopically normal mucosa, diffuse erythema, nodules, pseudotumors, erosions and ulcers. The bioptic detection of intranuclear inclusions is the hallmark of CMV infection. Most gastrointestinal CMV infection responds well to ganciclovir. We present endoscopic and histopathological features of CMV gastritis in a 71 year old woman receiving long-term prednisolone for pemphigus vulgaris.