Open AccessAssessing the yield and safety of endoscopy in acute graft-vs-host disease after hematopoietic stem cell transplant
Author(s) -
Anand Rajan,
Harry Trieu,
Peiguo Chu,
James Lin,
Trilokesh D. Kidambi
Publication year - 2020
Publication title -
world journal of gastrointestinal endoscopy
Language(s) - English
Resource type - Journals
ISSN - 1948-5190
DOI - 10.4253/wjge.v12.i10.341
Subject(s) - medicine , esophagogastroduodenoscopy , gastroenterology , endoscopy , hematopoietic stem cell transplantation , perforation , malignancy , nausea , vomiting , sigmoidoscopy , complication , neutropenia , surgery , disease , cancer , colonoscopy , chemotherapy , materials science , colorectal cancer , punching , metallurgy
Acute gastrointestinal (GI) graft- vs -host disease (aGVHD) is the most complication of hematopoietic stem cell transplant (HSCT) in patients with hematologic malignancy. Limited data exists on endoscopic evaluation of GVHD in post-HSCT patients with differing GI symptoms. Further, the diagnostic value of gross endoscopic findings as well as the safety of endoscopy in this commonly thrombocytopenic and neutropenic patient population remains unclear.