Open AccessPrior transfusion of umbilical cord mesenchymal stem cells can effectively alleviate symptoms of motion sickness in mice through interleukin 10 secretion
Author(s) -
Huasu Zhu,
Li Dong,
Cong Liu,
Jinxian Huang,
Shanshan Chen,
Lan-Bo Li,
Qing Shi,
Xiuli Ju
Publication year - 2021
Publication title -
world journal of stem cells
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.907
H-Index - 18
ISSN - 1948-0210
DOI - 10.4252/wjsc.v13.i2.177
Subject(s) - umbilical cord , mesenchymal stem cell , medicine , secretion , stem cell , immunology , interleukin , pathology , cytokine , microbiology and biotechnology , biology
Motion sickness (MS) is a disease that occurs during unbalanced movement, characterized by gastrointestinal symptoms and autonomic nervous system activation. Current clinical treatments for MS are limited. Recent evidence indicates that the levels of pro-inflammatory cytokines increase during MS and are associated with an inner ear immune imbalance. In the present study, mesenchymal stem cells (MSCs) have been shown to exert strong immuno-suppressive effects.