Open AccessMKK7-mediated phosphorylation of JNKs regulates the proliferation and apoptosis of human spermatogonial stem cells
Author(s) -
Zeng-Hui Huang,
Chuan Huang,
Xi-Ren Ji,
Wenjun Zhou,
Xuefeng Luo,
Qian Liu,
Yawen Tang,
Fei Gong,
Wenbing Zhu
Publication year - 2021
Publication title -
world journal of stem cells
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.907
H-Index - 18
ISSN - 1948-0210
DOI - 10.4252/wjsc.v13.i11.1797
Subject(s) - phosphorylation , cell sorting , apoptosis , cell growth , gene knockdown , microbiology and biotechnology , kinase , downregulation and upregulation , blot , small interfering rna , biology , transfection , cell culture , gene , flow cytometry , biochemistry , genetics
Human spermatogonial stem cells (SSCs) are the basis of spermatogenesis. However, little is known about the developmental regulatory mechanisms of SSC due to sample origin and species differences.