Open AccessApplication of dental stem cells in three-dimensional tissue regeneration
Author(s) -
HuiYi Hsiao,
Chung-Yi Nien,
HsiangHsi Hong,
MingHuei Cheng,
TzungHai Yen
Publication year - 2021
Publication title -
world journal of stem cells
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.907
H-Index - 18
ISSN - 1948-0210
DOI - 10.4252/wjsc.v13.i11.1610
Subject(s) - stem cell , dental follicle , dental pulp stem cells , dental papilla , periodontal ligament stem cells , tissue engineering , regeneration (biology) , stem cell transplantation for articular cartilage repair , progenitor cell , adult stem cell , amniotic stem cells , microbiology and biotechnology , biology , medicine , pathology , endothelial stem cell , biomedical engineering , pulp (tooth) , alkaline phosphatase , in vitro , odontoblast , biochemistry , enzyme
Dental stem cells can differentiate into different types of cells. Dental pulp stem cells, stem cells from human exfoliated deciduous teeth, periodontal ligament stem cells, stem cells from apical papilla, and dental follicle progenitor cells are five different types of dental stem cells that have been identified during different stages of tooth development. The availability of dental stem cells from discarded or removed teeth makes them promising candidates for tissue engineering. In recent years, three-dimensional (3D) tissue scaffolds have been used to reconstruct and restore different anatomical defects. With rapid advances in 3D tissue engineering, dental stem cells have been used in the regeneration of 3D engineered tissue. This review presents an overview of different types of dental stem cells used in 3D tissue regeneration, which are currently the most common type of stem cells used to treat human tissue conditions.