Open AccessHuman mesenchymal stem cells derived from umbilical cord and bone marrow exert immunomodulatory effects in different mechanisms
Author(s) -
Youngseok Song,
Jung-Yeon Lim,
Taekyu Lim,
Keon-Il Im,
Nayoun Kim,
Yoonho Nam,
YoungWoo Jeon,
Jong Chul Shin,
Hyun Sun Ko,
In Yang Park,
Seok-Goo Cho
Publication year - 2020
Publication title -
world journal of stem cells
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.907
H-Index - 18
ISSN - 1948-0210
DOI - 10.4252/wjsc.v12.i9.1032
Subject(s) - mesenchymal stem cell , tumor necrosis factor alpha , immunology , cytokine , bone marrow , cancer research , cell therapy , medicine , stem cell , biology , microbiology and biotechnology , pathology
Mesenchymal stem cells (MSCs) are an attractive tool to treat graft-versus-host disease because of their unique immunoregulatory properties. Although human bone marrow-derived MSCs (BM-MSCs) were the most widely used MSCs in cell therapy until recently, MSCs derived from human umbilical cords (UC-MSCs) have gained popularity as cell therapy material for their ethical and noninvasive collection.