Open AccessSafety of menstrual blood-derived stromal cell transplantation in treatment of intrauterine adhesion
Author(s) -
Qiyuan Chang,
Siwen Zhang,
Pingping Li,
Zhengwei Yuan,
Jichun Tan
Publication year - 2020
Publication title -
world journal of stem cells
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.907
H-Index - 18
ISSN - 1948-0210
DOI - 10.4252/wjsc.v12.i5.368
Subject(s) - medicine , transplantation , stromal cell , andrology , toxicity , chronic toxicity , adverse effect
Intrauterine adhesion (IUA) can cause serious damage to women's reproductive health, yet current treatment methods are difficult to achieve satisfactory results. In our previous studies, we demonstrated that menstrual-derived stromal stem cells (MenSCs), with high proliferative capacity and self-renewal ability, have a powerful therapeutic effect in patients with severe IUA. However, safety assessment of MenSCs transplantation is essential for its further application.