Open AccessNeurotrophic effects of dental pulp stem cells in repair of peripheral nerve after crush injury
Author(s) -
Dian-Ri Wang,
Yuhao Wang,
Jian Pan,
Weidong Tian
Publication year - 2020
Publication title -
world journal of stem cells
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.907
H-Index - 18
ISSN - 1948-0210
DOI - 10.4252/wjsc.v12.i10.1196
Subject(s) - dental pulp stem cells , neurotrophic factors , nestin , glial cell line derived neurotrophic factor , sciatic nerve , neurotrophin , microbiology and biotechnology , crush injury , peripheral nerve injury , neural crest , regeneration (biology) , neural stem cell , stem cell , medicine , biology , anatomy , surgery , embryo , receptor
Nerve diseases and injuries, which are usually accompanied by motor or sensory dysfunction and disorder, impose a heavy burden upon patients and greatly reduce their quality of life. Dental pulp stem cells (DPSCs), derived from the neural crest, have many characteristics that are similar to those of neural cells, indicating that they can be an ideal source for neural repair.