Open AccessMiR-301a promotes embryonic stem cell differentiation to cardiomyocytes
Author(s) -
Lixiao Zhen,
Yuying Gu,
Qian Zhao,
Hongyu Zhu,
Jinhui Lv,
Shujun Li,
Zhen Xu,
Li Li,
Zuoren Yu
Publication year - 2019
Publication title -
world journal of stem cells
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.907
H-Index - 18
ISSN - 1948-0210
DOI - 10.4252/wjsc.v11.i12.1130
Subject(s) - embryonic stem cell , microbiology and biotechnology , embryoid body , mef2c , stem cell , biology , cellular differentiation , pi3k/akt/mtor pathway , adult stem cell , transcription factor , signal transduction , gene , genetics
Cardiovascular disease is the leading cause of death worldwide. Tissue repair after pathological injury in the heart remains a major challenge due to the limited regenerative ability of cardiomyocytes in adults. Stem cell-derived cardiomyocytes provide a promising source for the cell transplantation-based treatment of injured hearts.