Open AccessIntrahepatic therapy for liver-dominant metastatic colorectal cancer
Author(s) -
Kerlijne De Groote,
Hans Prenen
Publication year - 2015
Publication title -
world journal of gastrointestinal oncology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 26
ISSN - 1948-5204
DOI - 10.4251/wjgo.v7.i9.148
Subject(s) - medicine , colorectal cancer , selective internal radiation therapy , chemotherapy , oncology , radiation therapy , disease , cancer , metastasis , gastroenterology , hepatocellular carcinoma
In patients with metastatic colorectal cancer, the liver is the most common site of metastatic disease. In patients with liver-dominant disease, consideration needs to be given to locoregional treatments such as hepatic arterial infusion chemotherapy, transarterial chemoembolisation and selective internal radiation therapy because hepatic metastases are a major cause of liver failure especially in chemorefractory disease. In this review we provide insights on the published literature for locoregional treatment of liver metastases in metastatic colorectal cancer.