Open AccessComplete clinical response of liver metastasis after chemotherapy: To resect or not?
Author(s) -
José Manuel Ramia-Ángel,
Roberto de la Plaza,
José E. Quiñones Sampedro
Publication year - 2011
Publication title -
world journal of gastrointestinal oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 26
ISSN - 1948-5204
DOI - 10.4251/wjgo.v3.i7.107
Subject(s) - medicine , chemotherapy , metastasis , pathological , complete response , oncology , cancer
This paper aims to update the therapeutical strategies in liver metastasis with complete clinical response (CCR) after chemotherapy and to determine if surgery is always necessary after CCR. The aim of chemotherapy is to achieve a good clinical response rather than CCR of liver metastasis. The CCR of liver metastasis after chemotherapy cannot be considered synonymous with a cure. The resection of the hepatic segment where there was hepatic metastases with CCR after chemotherapy theoretically prevents recurrence, improves survival and makes it possible to confirm whether there has been a complete pathological response. However, the medical literature about this topic is scarce and sometimes contradictory.