Open AccessGastric cancer,helicobacter pyloriinfection and other risk factors
Author(s) -
Lorenzo Fuccio,
Leonardo Henry Eusebi,
Franco Bazzoli
Publication year - 2010
Publication title -
world journal of gastrointestinal oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 26
ISSN - 1948-5204
DOI - 10.4251/wjgo.v2.i9.342
Subject(s) - medicine , helicobacter pylori , cancer , risk factor , disease , incidence (geometry) , gastroenterology , helicobacter pylori infection , intensive care medicine , physics , optics
Gastric cancer incidence is declining. However, it is too early to consider this neoplastic disease as rare and the worldwide mortality rate still remains high. Several risk factors have been identified for non-cardia gastric cancer and primary prevention is feasible since most of the risk factors can be removed. Helicobacter pylori eradication treatment reduces but does not abolish gastric cancer risk. Indeed, gastric cancer is a multifactorial disease and removing one factor does not therefore prevent all cases. Endoscopic surveillance is still needed, especially in subjects at higher risk. The definition of high-risk patients will be the future challenge as well as identifying the best surveillance strategy for such patients.