Open AccessPositron emission tomography as predictor of rectal cancer response during or following neoadjuvant chemoradiation
Author(s) -
Shane Hopkins,
Marwan Fakih,
Guangxiao Yang
Publication year - 2010
Publication title -
world journal of gastrointestinal oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 26
ISSN - 1948-5204
DOI - 10.4251/wjgo.v2.i5.213
Subject(s) - medicine , positron emission tomography , colorectal cancer , neoadjuvant therapy , standardized uptake value , nuclear medicine , radiology , cancer , medical physics , oncology , breast cancer
Positron emission tomography (PET) shows great promise as a tool to evaluate the effectiveness of rectal cancer neoadjuvant therapy as it has demonstrated high predictive value in several studies. Creating a standardized method of using PET has the potential to reduce ineffective treatments. However, relevant studies have been heterogenous in approach, making any unified standard difficult to establish. PET related parameters used to assess treatment response include magnitude and change of standard uptake value, total lesion glycolysis, and visual response. Finding the best evaluation interval and parameters to use for interpreting PET results in the neo-adjuvant treatment of rectal cancer needs additional study.