Open AccessScoparone inhibits pancreatic cancer through PI3K/Akt signaling pathway
Author(s) -
Na Li,
Fan Yang,
Dongyan Liu,
Jintao Guo,
Nan Ge,
Siyu Sun
Publication year - 2021
Publication title -
world journal of gastrointestinal oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 26
ISSN - 1948-5204
DOI - 10.4251/wjgo.v13.i9.1164
Subject(s) - pancreatic cancer , cell cycle , cancer research , pi3k/akt/mtor pathway , nude mouse , apoptosis , cell growth , medicine , cancer , signal transduction , biology , microbiology and biotechnology , biochemistry
Pancreatic cancer is a highly malignant tumor of the gastrointestinal system whose emerging resistance to chemotherapy has necessitated the development of novel antitumor treatments. Scoparone, a traditional Chinese medicine monomer with a wide range of pharmacological properties, has attracted considerable attention for its antitumor activity.