Open AccessEfficacy and toxicity of capecitabine combined with intensity-modulated radiotherapy after D1/D2 lymph node dissection in patients with gastric cancer
Author(s) -
Xin Wang,
Weihu Wang,
Shulian Wang,
Yong-Wen Song,
Yueping Liu,
Yuan Tang,
Ning Li,
Wenyang Liu,
Hui Fang,
Ye-Xiong Li,
Dongbing Zhao,
Yihebali Chi,
Lin Yang,
Jing Jin
Publication year - 2021
Publication title -
world journal of gastrointestinal oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 26
ISSN - 1948-5204
DOI - 10.4251/wjgo.v13.i10.1532
Subject(s) - medicine , capecitabine , radiation therapy , chemoradiotherapy , clinical endpoint , adenocarcinoma , lymph node , surgery , cancer , randomized controlled trial , colorectal cancer
Adjuvant chemoradiotherapy (ACRT) with oral capecitabine and intensity-modulated radiotherapy (IMRT) were well tolerated in a phase I study in patients who had undergone partial or total gastrectomy for locally advanced gastric cancer (GC). This phase II study aimed to further determine the efficacy and toxicity of this combination after radical resection and D1/D2 lymph node dissection (LND) for patients with locally advanced GC.