Open AccessSynergistic anti-liver cancer effects of curcumin and total ginsenosides
Author(s) -
Zhe Deng,
Xiaoyan Xu,
Fenny Yunita,
Qing Zhou,
Yongrong Wu,
Ya-Han Hu,
Zhiqi Wang,
Xuefei Tian
Publication year - 2020
Publication title -
world journal of gastrointestinal oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 26
ISSN - 1948-5204
DOI - 10.4251/wjgo.v12.i10.1091
Subject(s) - curcumin , medicine , traditional medicine , liver cancer , pharmacology , cancer
Liver cancer is the sixth most frequently occurring cancer in the world and the fourth most common cause of cancer mortality. The pathogenesis of liver cancer is closely associated with inflammation and immune response in the tumor microenvironment. New therapeutic agents for liver cancer, which can control inflammation and restore cellular immunity, are required. Curcumin (Cur) is a natural anti-inflammatory drug, and total ginsenosides (TG) are a commonly used immunoregulatory drug. Of note, both Cur and TG have been shown to exert anti-liver cancer effects.