Open AccessGlycerophospholipids pathways and chromosomal instability in gastric cancer: Global lipidomics analysis
Author(s) -
Cheng-Yu Hung,
TaSen Yeh,
ChengKun Tsai,
RenChin Wu,
YingChieh Lai,
Meng-Han Chiang,
KuanYing Lu,
ChiaNi Lin,
MeiLing Cheng,
Gigin Lin
Publication year - 2019
Publication title -
world journal of gastrointestinal oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.924
H-Index - 26
ISSN - 1948-5204
DOI - 10.4251/wjgo.v11.i3.181
Subject(s) - lipidomics , glycerophospholipid , phosphocholine , phosphatidylethanolamine , cancer , metabolomics , sphingomyelin , medicine , biology , microbiology and biotechnology , biochemistry , bioinformatics , phospholipid , phosphatidylcholine , membrane , cholesterol
Based on the breakthrough of genomics analysis, The Cancer Genome Atlas Research Group recently proposed an integrative genomic analysis, dividing gastric cancer (GC) into four subtypes, characterized by the chromosomal instability (CIN) status. However, the CIN status of GC is still vaguely characterized and lacking the valuable easy-to-use CIN markers to diagnosis in molecular and histological detection.