Open AccessStatistical proof of Helicobacter pylori eradication in preventing metachronous gastric cancer after endoscopic resection in an East Asian population
Author(s) -
Mohsen Karbalaei,
Masoud Keikha
Publication year - 2022
Publication title -
world journal of gastrointestinal surgery
Language(s) - English
Resource type - Journals
ISSN - 1948-9366
DOI - 10.4240/wjgs.v14.i8.867
Subject(s) - helicobacter pylori , medicine , intestinal metaplasia , gastroenterology , cancer , antrum , population , endoscopic mucosal resection , surgery , stomach , endoscopy , environmental health
We conducted a comprehensive literature review and meta-analysis study on the efficacy of Helicobacter pylori ( H. pylori ) eradication in preventing metachronous gastric cancer after endoscopic resection among an East Asian population. Our results showed that the eradication of this pathogen significantly reduced the risk of susceptibility to metachronous gastric cancer in these patients. However, based on the available evidence, several factors such as increasing age, severe atrophy in the corpus and antrum, and intestinal metaplasia all may increase the risk of metachronous gastric cancer in H. pylori eradicated patients.