Open AccessMalignant transformation of hepatocellular adenoma in a young female patient after ovulation induction fertility treatment: A case report
Author(s) -
Juan Glinka,
Rodrigo Sánchez Clariá,
Eugenia Fratai,
Juan Carlos Spina,
Eduardo Müllen,
Victoria Ardiles,
Oscar Mazza,
Juan Pekolj,
Martín de Santibañes,
Eduardo de Santibáñes
Publication year - 2019
Publication title -
world journal of gastrointestinal surgery
Language(s) - English
Resource type - Journals
ISSN - 1948-9366
DOI - 10.4240/wjgs.v11.i4.229
Subject(s) - medicine , malignancy , hepatocellular adenoma , infertility , asymptomatic , focal nodular hyperplasia , ovulation induction , magnetic resonance imaging , malignant transformation , adenoma , surgery , radiology , hepatocellular carcinoma , hormone , pregnancy , pathology , ovulation , biology , genetics
Hepatocellular adenoma (HCA) is a rare benign liver tumor usually affecting young women with a history of prolonged use of hormonal contraception. Although the majority is asymptomatic, a low proportion may have significant complications such as bleeding or malignancy. Despite responding to the hormonal stimulus, the desire for pregnancy in patients with small HCA is not contraindicated. However, through this work we demonstrate that intensive hormonal therapies such as those used in the treatment of infertility can trigger serious complications.