Open AccessAcquired segmental colonic hypoganglionosis in an adult Caucasian male: A case report
Author(s) -
Allan Mf Kwok,
Andrew Still,
Kimberly Anne Hart
Publication year - 2019
Publication title -
world journal of gastrointestinal surgery
Language(s) - English
Resource type - Journals
ISSN - 1948-9366
DOI - 10.4240/wjgs.v11.i2.101
Subject(s) - medicine , etiology , abdominal pain , descending colon , vomiting , biopsy , sigmoid colon , surgery , disease , pathology , rectum
Hypoganglionosis is a rare condition that most often presents with abnormal gastrointestinal transit and usually arises in early childhood or adolescence. Two types have been described (Type I and Type II). The adult-onset form (acquired hypoganglionosis) is extremely uncommon and is thought to arise due to cellular remodelling as a result of chronic inflammation. It differs from Hirschprung's disease in that there is a reduction in ganglion cells in the colonic neural plexuses as opposed to being completely absent.