Open AccessRole of adiponectin and some other factors linking type 2 diabetes mellitus and obesity
Author(s) -
Chandra Kanti Chakraborti
Publication year - 2015
Publication title -
world journal of diabetes
Language(s) - English
Resource type - Journals
ISSN - 1948-9358
DOI - 10.4239/wjd.v6.i15.1296
Subject(s) - adiponectin , medicine , obesity , type 2 diabetes mellitus , diabetes mellitus , adipocyte , incidence (geometry) , type 2 diabetes , disease , endocrinology , gerontology , insulin resistance , adipose tissue , physics , optics
Because of the intimate association of obesity with type 2 diabetes mellitus (T2DM), during the last two decades, extensive research work is being conducted to find out whether the coexistence of the two is a simple association or there is a positive correlating link between the two. In this article, an attempt has been made to collect and analyse the recent developments in this field and to arrive at a conclusion on the subject. The possible role of several important factors (obtained from adipocytes/not of adipocyte origin) in linking the two has been discussed in detail. Some of the agents, specifically adiponectin, are beneficial (i.e., reduce the incidence of both), while others are harmful (i.e., increase their incidence). From the analysis, it appears that obesity and T2DM are intimately linked.