Open AccessMultidrug Delivery Systems with Single Formulation——Current status and Future Perspective
Author(s) -
Takatoshi Okuda,
Satoru Kidoaki
Publication year - 2012
Publication title -
journal of biomaterials and nanobiotechnology
Language(s) - English
Resource type - Journals
eISSN - 2158-7043
pISSN - 2158-7027
DOI - 10.4236/jbnb.2012.31007
Subject(s) - drug delivery , computer science , nanobiotechnology , risk analysis (engineering) , biochemical engineering , nanotechnology , medicine , engineering , materials science , nanoparticle
Development of new way and system for multidrug delivery has recently attracted much attention and became one of major issue in drug delivery research. Although this research field is still immature compared to the single drug delivery system, intensive efforts have recently been devoted by researchers in order to realize more efficient, functional, and safe combination therapy using multiple drugs or agents. In this review article, we outline several targets in terms of application for biochemical modulation together with various concrete attempts of simultaneous and sequential delivery of multiple drugs or agents with single formulation. Finally, we will also summarize the possible contribution of biomaterial sciences and nanobiotechnology for improvement of future multidrug delivery system