Open AccessThe Differential Effects of Chronic Alcohol and Cigarette Smoke Exposures on Cognitive-Behavioral Dysfunction in Long Evans Rats
Author(s) -
Emine Yalçın,
Büşra Delikkaya,
William Pelit,
Ming Tong,
Suzanne M. de la Monte,
Sharon Rounds
Publication year - 2022
Publication title -
journal of behavioral and brain science
Language(s) - English
Resource type - Journals
eISSN - 2160-5874
pISSN - 2160-5866
DOI - 10.4236/jbbs.2022.129024
Subject(s) - cognition , cigarette smoke , medicine , smoke , psychology , clinical psychology , psychiatry , environmental health , chemistry , organic chemistry
Chronic heavy alcohol consumption and daily cigarette smoking are the most prevalent substance use problems in the U.S., including Veterans. Excessive alcohol use causes neurocognitive and behavioral deficits that can be linked to neurodegeneration. Similarly, preclinical and clinical data suggest that smoking also leads to brain atrophy. This study examines the differential and additive effects of alcohol and cigarette smoke (CS) exposures on cognitive-behavioral function.