Open AccessSynthesis and Biological Evaluation of Novel 6-(3-(4,5-Dihydro-1,5-diphenyl-1<i>H</i>-pyrazol-3-yl)phenylamino) Pyridazin-3(2H)-one Derivatives
Author(s) -
Shrikrishna D. Tupare,
Satish A. Dake,
Santosh V. Nalage,
Sidhanath V. Bhosale,
R. D. Ingle,
Rajendra P. Pawar
Publication year - 2012
Publication title -
international journal of organic chemistry
Language(s) - English
Resource type - Journals
eISSN - 2161-4695
pISSN - 2161-4687
DOI - 10.4236/ijoc.2012.24051
Subject(s) - pyrazoline , elemental analysis , chemistry , pyrazole , proton nmr , biological activity , nuclear chemistry , combinatorial chemistry , medicinal chemistry , stereochemistry , organic chemistry , biochemistry , in vitro
Pyrazoles are important nitrogen containing 5-membered heterocyclic compounds. Numerous pyrazoline derivatives have been found to possess considerable biological activities, which stimulated the research activity in this field. Several 1,3,5-Triphenyl-1H-pyrazole containing 6-aminopyridazin-3(2H)-one derivatives has been synthesized. These new compounds were characterized using IR, 1H-NMR and Mass spectra and Elemental analysis. They possess some potent biological activities. Therefore biological screening of novel compounds has been also done