Open AccessAntagonism of Angiotensin II AT1 Receptor and Silencing of CD44 Gene Expression Inhibit Cardiac Fibroblast Activation via Modulating TGF-<i>β</i>1/Smad Signaling Pathway
Author(s) -
Feng Bai,
Gang Yang,
Joshua Eskew,
Ning-Ping Wang,
Himangshu S. Bose,
Zhiqing Zhao
Publication year - 2020
Publication title -
advances in bioscience and biotechnology
Language(s) - English
Resource type - Journals
eISSN - 2156-8502
pISSN - 2156-8456
DOI - 10.4236/abb.2020.114010
Subject(s) - angiotensin ii , cardiac fibrosis , gene silencing , small interfering rna , angiotensin ii receptor type 1 , receptor , cd44 , transforming growth factor , fibroblast , microbiology and biotechnology , smad , biology , signal transduction , myocardial fibrosis , fibrosis , medicine , endocrinology , chemistry , transfection , cell , cell culture , gene , biochemistry , genetics