Open AccessDoes the contraceptive pill influence peak nasal inspiratory flow values?
Author(s) -
Giancarlo Ottaviano,
Erich Cosmi,
Valentina Iacono,
Bruno Scarpa,
Alberto Staffieri,
Glenis Scadding
Publication year - 2014
Publication title -
rhinology (amsterdam. online)/rhinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.275
H-Index - 57
eISSN - 1996-8604
pISSN - 0300-0729
DOI - 10.4193/rhino14.004
Subject(s) - medicine , pill , estrogen , oral contraceptive pill , mucous membrane of nose , anesthesia , obstetrics , family planning , population , research methodology , anatomy , pharmacology , environmental health
Background: Early oral contraceptive pills (OCP) had higher estrogen levels and have been thought to cause nasal obstruction in about 40% of women users. A recent small study conducted on women taking OCP showed no significant effects on nasal patency. The aim of the present study was to analyse in a large number of volunteers if Peak Nasal Inspiratory Flow (PNIF) values could be influenced by modern OCP. Methodology: PNIF was measured in 257 women (from 14 to 51 years old), divided into two groups: the study group composed of 109 healthy women taking modern OCP; the control group composed of 148 healthy women who did not take OCP. 9 women in the study group were excluded because of allergic disease, 248 females were finally considered. Data were statistically analysed and figures/tables were produced to see the effect of OCP on PNIF. Results: The present study could not show any effect of OCP on nasal function. Moreover, while height influenced PNIF in both groups, age was not statistically significant. Conclusion: From the present study, it seems that OCP could have no effects on nasal airflow, confirming that modern OCP with lower estrogen doses should not affect nasal mucosa or nasal patency.