Open AccessMono-allergic and poly-allergic rhinitis patients have comparable numbers of mucosal Foxp3+CD4+ T lymphocytes
Author(s) -
Barbara A. Muller,
Susanne M. Reinartz,
Danielle van Egmond,
E. J. J. de Groot,
Wytske Fokkens,
Cornelis M. van Drunen
Publication year - 2014
Publication title -
rhinology (amsterdam. online)/rhinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.275
H-Index - 57
eISSN - 1996-8604
pISSN - 0300-0729
DOI - 10.4193/rhino13.223
Subject(s) - medicine , sensitization , provocation test , nasal provocation test , house dust mite , immunology , allergen , mite , allergy , foxp3 , pollen , dermatology , immune system , pathology , biology , ecology , botany , alternative medicine
We previously found that allergic rhinitis patients with an isolated pollen sensitization responded more strongly to a nasal provocation with grass pollen (GP) than patients who had an additional house dust mite (HDM) sensitization. To elucidate this phenomenon, we investigated the dynamics of Foxp3+CD4+ T lymphocytes in allergic rhinitis patients with distinct allergen sensitizations.