Predictive significance of Charcot-Leyden Crystal mRNA levels in nasal brushing for nasal polyp recurrence | Zendy

Sihan Qi | Zendy; Bing Yan | Zendy; C Liu | Zendy; Chong Wang | Zendy; Luo Zhang | Zendy

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Predictive significance of Charcot-Leyden Crystal mRNA levels in nasal brushing for nasal polyp recurrence

Author(s) -

Sihan Qi,

Bing Yan,

C Liu,

Chong Wang,

Luo Zhang

Publication year - 2019

Publication title -

rhinology journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.275

H-Index - 57

eISSN - 1996-8604

pISSN - 0300-0729

DOI - 10.4193/rhin19.296

Subject(s) - medicine , nasal polyps , chronic rhinosinusitis , endoscopic sinus surgery , gastroenterology , biomarker , logistic regression , endoscopy , clinical significance , surgery , pathology , biochemistry , chemistry

Tissue eosinophils have been shown to be associated with polyp recurrence in chronic rhinosinusitis with nasal polyps (CRSwNP). We addressed whether the mRNA levels of Charcot-Leyden Crystal (CLC) in nasal brushing samples, a molecule mainly released from activated eosinophils, could serve as an effective non-invasive biomarker to predict polyp recurrence.

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