Broncho-vaxom alleviates persistent allergic rhinitis in patients by improving Th1/Th2 cytokine balance of nasal mucosa | Zendy

Qinglin Meng | Zendy; Peng Li | Zendy; Y. Li | Zendy; J. Chen | Zendy; Li Wang | Zendy; Ling He | Zendy; Jianteng Xie | Zendy; Xiang Gao | Zendy

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Broncho-vaxom alleviates persistent allergic rhinitis in patients by improving Th1/Th2 cytokine balance of nasal mucosa

Author(s) -

Qinglin Meng,

Peng Li,

Y. Li,

J. Chen,

Li Wang,

Ling He,

Jianteng Xie,

Xiang Gao

Publication year - 2019

Publication title -

rhinology journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.275

H-Index - 57

eISSN - 1996-8604

pISSN - 0300-0729

DOI - 10.4193/rhin19.161

Subject(s) - medicine , rhinorrhea , placebo , mucous membrane of nose , nasal lavage , gastroenterology , nasal administration , respiratory tract , nasal congestion , loratadine , respiratory system , allergy , nose , immunology , surgery , pathology , alternative medicine

Probiotics are mainly distributed in the mucosal system and have the ability to enhance mucosal barrier function and regulate immune responses. Broncho-Vaxom (BV), as a probiotic, has been applied to patients suffering from respiratory tract infections, but its potential effectiveness in allergic rhinitis (AR) has not been evaluated in human. This study aimed to investigate the clinical efficacy of BV in patients with persistent AR and to elucidate the underlying cellular mechanisms.

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