Open AccessExploring the association between ingestion of foods with higher potential salicylate content and symptom exacerbation in chronic rhinosinusitis. Data from the National Chronic Rhinosinusitis Epidemiology Study
Author(s) -
Carl Philpott,
R. A. Smith,
C.R. DaviesHusband,
Sally Erskine,
Allan Clark,
Amy Welch,
Chris Hopkins,
Sean Carrie,
Jaydip Ray,
Sunkaraneni,
Naveed Kara,
Nirmal Kumar,
Alasdair Robertson,
Shahram Anari,
Robert Almeyda,
A. O. A. Wilson
Publication year - 2019
Publication title -
rhinology (amsterdam. online)/rhinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.275
H-Index - 57
eISSN - 1996-8604
pISSN - 0300-0729
DOI - 10.4193/rhin19.027
Subject(s) - medicine , exacerbation , epidemiology , asthma , sinusitis , ingestion , incidence (geometry) , nasal polyps , population , chronic rhinosinusitis , environmental health , immunology , physics , optics
Pharmacological salicylates are known to trigger respiratory exacerbations in patients with Non-Steroidal Exacerbated Respiratory Disease (N-ERD), a specific phenotype of Chronic Rhinosinusitis (CRS) and asthma. The impact of dietary sources of salicylates across subgroups of CRS is not well understood. The hypothesis is that in patients with nasal polyps present, there is likely to be a higher incidence of symptom exacerbation due to dietary salicylates regardless of any known response to pharmacological salicylate.