Open AccessThe presence of Interleukin-13 in nasal lavage may be a predictor of nasal polyposis in pediatric patients with cystic fibrosis
Author(s) -
Jamil Manji,
Andrew Thamboo,
Mark Tacey,
Cathie Garnis,
Neil K. Chadha
Publication year - 2018
Publication title -
rhinology (amsterdam. online)/rhinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.275
H-Index - 57
eISSN - 1996-8604
pISSN - 0300-0729
DOI - 10.4193/rhin17.007
Subject(s) - medicine , cystic fibrosis , otorhinolaryngology , cytokine , interleukin 13 , gastroenterology , nasal lavage , logistic regression , population , disease , immunology , interleukin , allergy , surgery , environmental health
Sinonasal disease is a common feature of cystic fibrosis (CF) and can cause significant morbidity in these patients. Our objective was to determine if CF individuals with concomitant nasal polyposis (NP) express a unique profile of inflammation and if so, whether these inflammatory cytokine mediators have predictive value in identifying these individuals for prompt management by an Otolaryngologist.