The presence of Interleukin-13 in nasal lavage may be a predictor of nasal polyposis in pediatric patients with cystic fibrosis | Zendy

Jamil Manji | Zendy; Andrew Thamboo | Zendy; Mark Tacey | Zendy; Cathie Garnis | Zendy; Neil K. Chadha | Zendy

Open Access

The presence of Interleukin-13 in nasal lavage may be a predictor of nasal polyposis in pediatric patients with cystic fibrosis

Author(s) -

Jamil Manji,

Andrew Thamboo,

Mark Tacey,

Cathie Garnis,

Neil K. Chadha

Publication year - 2018

Publication title -

rhinology journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.275

H-Index - 57

eISSN - 1996-8604

pISSN - 0300-0729

DOI - 10.4193/rhin17.007

Subject(s) - medicine , cystic fibrosis , otorhinolaryngology , cytokine , interleukin 13 , gastroenterology , nasal lavage , logistic regression , population , disease , immunology , interleukin , allergy , surgery , environmental health

Sinonasal disease is a common feature of cystic fibrosis (CF) and can cause significant morbidity in these patients. Our objective was to determine if CF individuals with concomitant nasal polyposis (NP) express a unique profile of inflammation and if so, whether these inflammatory cytokine mediators have predictive value in identifying these individuals for prompt management by an Otolaryngologist.

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