Open AccessThe effect of topical treatments for CRS on the sinonasal epithelial barrier
Author(s) -
Mahnaz Ramezanpour,
Anwar Rayan,
Jason Smith,
Sarah Vreugde
Publication year - 2017
Publication title -
rhinology (amsterdam. online)/rhinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.275
H-Index - 57
eISSN - 1996-8604
pISSN - 0300-0729
DOI - 10.4193/rhin16.284
Subject(s) - medicine , budesonide , fluorescein isothiocyanate , tonicity , hypertonic saline , barrier function , saline , paracellular transport , lactate dehydrogenase , tight junction , fluorescein , toxicity , saliva , pharmacology , biochemistry , inhalation , anesthesia , permeability (electromagnetism) , chemistry , biology , enzyme , membrane , physics , quantum mechanics , fluorescence , microbiology and biotechnology
Several topical treatments are used in the management of Chronic Rhinosinusitis (CRS), some of which the safety and efficacy has yet to be determined. The purpose of this study was to investigate the effect of commonly used topical treatments on the sinonasal epithelial barrier.