Association between the CTLA-4 EXON 1+49A/G Polymorphism and the Relapse of Grave’s Disease after ATD Withdrawal: A Meta-Analysis | Zendy

Xiao Jiang | Zendy; Houyuan Hu | Zendy; Zhiyong Fu | Zendy; Yongping Su | Zendy; Jirong Long | Zendy

Open Access

Association between the CTLA-4 EXON 1+49A/G Polymorphism and the Relapse of Grave’s Disease after ATD Withdrawal: A Meta-Analysis

Author(s) -

Xiao Jiang,

Houyuan Hu,

Zhiyong Fu,

Yongping Su,

Jirong Long

Publication year - 2022

Publication title -

acta endocrinologica (bucharest)

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.249

H-Index - 13

eISSN - 1843-066X

pISSN - 1841-0987

DOI - 10.4183/aeb.2022.324

Subject(s) - medicine , gastroenterology , meta analysis , genotype , graves' disease , subgroup analysis , cochrane library , confidence interval , polymorphism (computer science) , disease , genetics , biology , gene

The cytotoxic T lymphocyte-associated molecules-4 (CTLA-4) is related to the relapse of Graves' disease (GD) after anti-thyroid drugs (ATDs) withdrawal. We performed a meta-analysis to generate large-scale evidence on whether the CTLA-4 exon 1+49A/G polymorphism can predict the relapse of GD after ATDs withdrawal.

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