Iatrogenic Cushing’S Syndrome as a Consequence of Nasal Use of Betamethasone Spray During Pregnancy | Zendy

Ana Maria Scutelnicu | Zendy; Anca Maria Panaitescu | Zendy; Anne-Marie Ciobanu | Zendy; Nicolae Gică | Zendy; Radu Botezatu | Zendy; Gheorghe Peltecu | Zendy; Monica Livia Gheorghiu | Zendy

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Iatrogenic Cushing’S Syndrome as a Consequence of Nasal Use of Betamethasone Spray During Pregnancy

Author(s) -

Ana Maria Scutelnicu,

Anca Maria Panaitescu,

Anne-Marie Ciobanu,

Nicolae Gică,

Radu Botezatu,

Gheorghe Peltecu,

Monica Livia Gheorghiu

Publication year - 2020

Publication title -

acta endocrinologica (bucharest)

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.249

H-Index - 13

eISSN - 1843-066X

pISSN - 1841-0987

DOI - 10.4183/aeb.2020.511

Subject(s) - medicine , betamethasone , nasal spray , nasal administration , pregnancy , glucocorticoid , anesthesia , pharmacology , biology , genetics

Glucocorticoids (GC) are largely used for their anti-inflammatory and immunosuppressive effects. Until recently "local" administration (inhalation, topical, intra-articular, ocular and nasal) was considered devoid of important systemic side effects, but there is no administration form, dosing or treatment duration for which the risk of iatrogenic Cushing's syndrome (CS) and consequent adrenal insufficiency (AI) can be excluded with certainty.

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