Triiodothyronine Activates Glycerol-3-Phosphate Acyltransferase 3 via AGGTCA-Like-Direct-Repeat-4 Type Thyroid Hormone Response Element | Zendy

Luyao Zhao | Zendy; Yugo Iwasaki | Zendy; Bong-Heon Han | Zendy; J Wang | Zendy; Y Zhang | Zendy; Jun Han | Zendy; G Y Liu | Zendy; Xia Jiang | Zendy

Open Access

Triiodothyronine Activates Glycerol-3-Phosphate Acyltransferase 3 via AGGTCA-Like-Direct-Repeat-4 Type Thyroid Hormone Response Element

Author(s) -

Luyao Zhao,

Yugo Iwasaki,

Bong-Heon Han,

J Wang,

Y Zhang,

Jun Han,

G Y Liu,

Xia Jiang

Publication year - 2020

Publication title -

acta endocrinologica (bucharest)

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.249

H-Index - 13

eISSN - 1843-066X

pISSN - 1841-0987

DOI - 10.4183/aeb.2020.129

Subject(s) - thyroid hormone receptor , retinoid x receptor , electrophoretic mobility shift assay , triiodothyronine , hormone response element , luciferase , malic enzyme , microbiology and biotechnology , thyroid hormone receptor beta , dehydrogenase , nuclear receptor , biochemistry , biology , promoter , reporter gene , chemistry , enzyme , hormone , gene , gene expression , hormone receptor , transfection , transcription factor , genetics , estrogen receptor , cancer , breast cancer

Thyroid hormone participates in lipid metabolism regulation. However, the effects on triacyleride or triacylglycerol metabolism are complex and not fully clarified yet. In this study, we try to identify novel thyroid hormone-targeting lipogenic metabolic genes and analyze their molecular regulative mechanism.

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