Open AccessBeneficial effects of proximal intestinal bypass reconstruction on glucose metabolism in a type 2 diabetes animal model: a possible reconstruction strategy for diabetic gastric cancer patients
Author(s) -
Soo Min Ahn,
Woo Jin Hyung
Publication year - 2021
Publication title -
annals of surgical treatment and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.559
H-Index - 25
eISSN - 2288-6796
pISSN - 2288-6575
DOI - 10.4174/astr.2021.100.4.218
Subject(s) - medicine , endocrinology , insulin , type 2 diabetes , pdx1 , diabetes mellitus , islet
Proximal intestinal bypass (PIB), such as Billroth II or Roux-en-Y gastrojejunostomy after curative distal gastrectomy for gastric cancer induces beneficial effects on glycemic control in patients with type 2 diabetes. We aimed to characterize the long-term evolution of pancreatic beta cells and insulin signaling in target tissue after a PIB procedure.