Open AccessSpontaneous Remission of Primary Hyperparathyroidism in a Patient with Neurofibromatosis Type 1: Case Report
Author(s) -
França MM
Publication year - 2012
Publication title -
journal of clinical case reports
Language(s) - English
Resource type - Journals
ISSN - 2165-7920
DOI - 10.4172/2165-7920.1000156
Subject(s) - primary hyperparathyroidism , medicine , neurofibromatosis , omics , pediatrics , complete remission , hyperparathyroidism , bioinformatics , primary (astronomy) , spontaneous remission , surgery , pathology , alternative medicine , biology , physics , chemotherapy , astronomy
Neurofibromatosis type 1 (NF1) is an autosomal dominant multisystem disorder affecting approximately 1 in 3500 individuals. Patients with the disorder can develop carcinoid tumors, medullary thyroid carcinoma, pheochromocytoma and tumor of the hypothalamus. The association of NF1 with Primary Hyperparathyroidism (HPP) is very rare. We report a 56-year-old woman with NF1 who was referred to our service because of nephrolithiasis. Physical examination revealed the characteristic signs of NF1, and her laboratory calcium profile was compatible with HPP. The patient was referred for parathyroidectomy, but during the surgical work-up she underwent spontaneous remission of her HPP. This case is significant not only for the rarity of this presentation in NF1 patients, but also because of the spontaneous remission of HPP