Open AccessBone Health in HIV-Infected Children, Adolescents and Young Adults: A Systematic Review
Author(s) -
Stephen M. Arpadi,
Stephanie Shiau,
Charlotte Marx-Arpadi,
Michael T. Yin
Publication year - 2014
Publication title -
journal of aids and clinical research
Language(s) - English
Resource type - Journals
ISSN - 2155-6113
DOI - 10.4172/2155-6113.1000374
Subject(s) - medicine , osteoporosis , pediatrics , peak bone mass , human immunodeficiency virus (hiv) , bone density , immunology
Children and adolescents, who either acquire HIV infection perinatally, from contaminated blood products or via sexual transmission early in life, have the greatest cumulative exposure to the negative direct and indirect effects of HIV infection and ART on bone, which may lead to increased lifetime risk for osteoporosis and fracture. We conducted a systematic review to evaluate the literature on bone health in children and adolescents with HIV.