Open AccessOral Nicotine Self-Administration in Rodents
Author(s) -
Allan C. Collins,
Şakire Pöğün,
Tanseli Nesil,
Lütfiye Kanıt
Publication year - 2012
Publication title -
journal of addiction research and therapy
Language(s) - Uncategorized
Resource type - Journals
ISSN - 2155-6105
DOI - 10.4172/2155-6105.s2-004
Subject(s) - nicotine , self administration , addiction , medicine , nicotine dependence , animal model , smokeless tobacco , psychology , pharmacology , physiology , psychiatry , tobacco use , environmental health , population
Nicotine addiction is a complex process that begins with self-administration. Consequently, this process has been studied extensively using animal models. A person is usually not called "smoker" if s/he has smoked for a week or a month in a lifetime; in general, a smoker has been smoking for many years. Furthermore, a smoker has free access to cigarettes and can smoke whenever she/he wants, provided there are no social/legal restraints. Subsequently, in an animal model of tobacco addiction, it will be desirable to expose the animal to free access nicotine for 24 hours/day for many weeks, starting at different stages of development.