Open AccessHemopexin: A Novel Anti-inflammatory Marker for Distinguishing COPD From Asthma
Author(s) -
Natasha A Winter,
Peter G. Gibson,
Michael Fricker,
Jodie L. Simpson,
Peter Wark,
Vanessa M. McDonald
Publication year - 2021
Publication title -
allergy, asthma and immunology research
Language(s) - English
Resource type - Journals
eISSN - 2092-7363
pISSN - 2092-7355
DOI - 10.4168/aair.2021.13.3.450
Subject(s) - hemopexin , medicine , biomarker , haptoglobin , copd , asthma , immunology , endotype , gastroenterology , biology , heme , biochemistry , enzyme
Systemic inflammatory biomarkers can improve diagnosis and assessment of chronic obstructive pulmonary disease (COPD) and asthma. We aimed to validate an airway disease biomarker panel of 4 systemic inflammatory biomarkers, α2-macroglobulin, ceruloplasmin, haptoglobin and hemopexin, to establish their relationship to airway disease diagnosis and inflammatory phenotypes and to identify an optimized biomarker panel for disease differentiation.