Open AccessInduction of apoptotic cell death in human bladder cancer cells by ethanol extract of Zanthoxylum schinifolium leaf, through ROS-dependent inactivation of the PI3K/Akt signaling pathway
Author(s) -
Cheol Park,
Eun Ok Choi,
Hyun Hwangbo,
Hyesook Lee,
JinWoo Jeong,
Min Han,
SungKwon Moon,
SeokJoong Yun,
Wun-Jae Kim,
GiYoung Kim,
HyeJin Hwang,
YouJin Jeon
Publication year - 2022
Publication title -
nutrition research and practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.506
H-Index - 34
eISSN - 2005-6168
pISSN - 1976-1457
DOI - 10.4162/nrp.2022.16.3.330
Subject(s) - apoptosis , biology , pi3k/akt/mtor pathway , reactive oxygen species , protein kinase b , microbiology and biotechnology , cancer research , biochemistry
Zanthoxylum schinifolium is traditionally used as a spice for cooking in East Asian countries. This study was undertaken to evaluate the anti-proliferative potential of ethanol extracts of Z. schinifolium leaves (EEZS) against human bladder cancer T24 cells.